全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

3-Hydroxy-2,2-bis(1H-pyrazol-1-yl)cyclopentanone

DOI: 10.1107/s1600536812007659

Full-Text   Cite this paper   Add to My Lib

Abstract:

The title compound, C11H12N4O2, was unexpectedly obtained in the reaction of α,α′-disubstituted cyclopentanone with 1,1,3,3-tetramethoxypropane in the presence of dioxane saturated with HCl. It belongs to a previously unknown class of gem-bihetaryl ketones which may be useful for screening of new substances with biological activity. In the studied structure, the cyclopentanone moiety adopts an envelope conformation, with the hydroxy-bearing C atom as the flap [deviation from basal plane = 0.643 (3) ]. The dihedral angle between the two pyrazole rings is 80.02 (8)°. In the crystal, inversion dimers are formed via a pair of O—H...N hydrogen bonds.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133