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Identifying the Common Target Genes for miR-21 Using Functional Enrichment Analysis

DOI: 10.7763/ijfcc.2013.v2.108

Keywords: Bioinformatics , database , functionalenrichment analysis , genes , microRNA.

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Abstract:

miR-21 is a well-studied microRNA which hasbeen implicated in many cancers. However, it is still noconsensus pertaining to its target genes. This study employed afunctional enrichment analysis to identify the common targetgenes for miR-21. Genomic data were compared using threedifferent algorithms to identify the common target genes formiR-21. Our results enhance the understanding of the targetgenes and the relevant cellular pathways for the miR-21-relateddiseases.

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