Development and Automation of Microturbulence Intensifying Systems and Biosynthesis Conditions in Bioreactors

Results of the investigation applying newly developed methods: a Stirring Intensity Measuring Device (SIMD), a counterflow mixing system, identification of the state of turbohypobiosis, counterflow bioreactor's design and a process controller BIO-3 have been analysed. Special attention has been given to the phenomena on the liquid-cell interface area. A combination of the above-mentioned methods with conventional ones does not provide the scale up and scale down of bioreactors when geometrical dissimilarity occurs. Special adjustment is necessary for each case and culture.