SISTEMIC CONGENITAL SYPHILIS CLINICAL AND BIOLOGICAL STUDY

One of the multisystemic infection transmitted to the fetus via the placenta is the congenital, syphilis caused by Treponema pallidum. High incidence of the disease led to routinely screening for all pregnant women. Clinical signs in neonatal period appear in the first 5 weeks of life, but signs of the disease may occur late, after the first 2 years of life. Diagnosis based on neonatal serologic testing is complicated by the transplacental transfer of maternal Ig antibodies, which can cause a positive test in the absence of infection. Three significant cases of congenital systemic syphilis treated in the Clinic of Neonatology are presented in this paperwork.