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A novel asymmetric synthesis of cinacalcet hydrochlorideDOI: 10.3762/bjoc.8.158 Keywords: asymmetric synthesis , (R)-tert-butanesulfinamide , cinacalcet hydrochloride , naphthyl ethyl sulfinamide , regioselective N-alkylation Abstract: A novel route to asymmetric synthesis of cinacalcet hydrochloride by the application of (R)-tert-butanesulfinamide and regioselective N-alkylation of the naphthyl ethyl sulfinamide intermediate is described.
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