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STUDY ON THE DEVELOPMENT OF HIGH YIELDING NEOMYCIN RESISTANT STRAIN OF STREPTOMYCES FRADIAE FOR IMPROVED PRODUCTION OF NEOMYCIN BY USING OPTIMAL LEVELS OF MINERALSKeywords: Neomycin , Streptomyces fradia , high yielding Neomycin resistant Strain , Fermentation Abstract: We have developed an ef icient high yielding neomycin resistant Strain of Streptomyces fradiae for improvedproduction of neomycin. Streptomyces fradie was submerged in the solution of10 ug/ml, 15 ug/ml, 20ug/ml,30 ug/ml,40 ug/ml,50 ug/ml, 60 ug/ml,70 ug/ml, 80 ug/ml, for five day for screeing out high yieldingNeomycin resistant Strain of Streptomyces fradiae . Streptomyces fradie in the solution of 70 ug/ml was thehigh yielding Neomycin resistant Strain of Streptomyces fradiae It was same observed as prevous authors thatoptimal levels of the elements Ca, Fe, and Zn per milliliter of a synthetic medium for neomycin production .K2HP04 was required at a concentration of 0.1% for maximal yield of n
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