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ISSN: 2333-9721
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EFFICACY EVALUATION OF AMPUCARE IN COMPARISON WITH SILVER SULFADIAZINE IN BURN WOUND HEALING IN RATS

Keywords: Burn , Silver sulfadiazine , Curcuma longa , Azadirachta indica.

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Abstract:

Plants have been used in ethno-medicine since many years and there has been an increasing interest inmedicinal plants and their traditional use. The present study compared ef icacy of Ampucare with that of silversulfadiazine in partial thickness burn in rats. Adult male Sprague_Dawley rats were divided into threegroups: control group (Normal saline treated group, Ampucare treated group and Silver sulfhdiazine treatedgroup. Complete healing of burn wound was observe in all the animals. A significant decrease in wound sizewas observed in Ampucare treated and Silver sulfadiazine treated group as compared to contraol group on day14. Both in control group and Silver sulfadiazine treated group not a single animal showed complete healing ofthe wound on day 14. Results suggested that Ampucare is significantly ef ective in treatment of partialthickness burn wounds than silver sulfadiazin

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