IN VITRO EVALUATION OF ANTIOXIDANT POTENTIAL OF VARIOUS EXTRACTS OF WHOLE PLANT OF Bridelia Scandens (Roxb) Willd.

The antioxidant activities of various extracts of whole plant of Bridelia scandens (Roxb) Willd, wasinvestigated in dif erent in-vitro methods. The antioxidant activity was evaluated by Total antioxidant activity(Phosphomolybdic acid method), FRAP assay with reference standard Ascorbate and total flavonoids contentrespectively. The methanolic extract of Bridelia scandens was the most ef ective total antioxidant activityamong the extracts. The IC50 values of the methanolic extract of Bridelia scandens and ascorbate was found tobe 100μg/ml and 410μg/ml respectively. The methanolic extract of Bridelia scandens was found more ef ectivein FRAP assay than that of petroleum ether and ethyl acetate extracts. But when compare to the all the threeextracts with ascorbate (standard), the methanolic extract of the Bridelia scandens showed the significantresult. The methanolic extract of Bridelia scandens contains high amount of flavonoids than that of other twoextracts. Moreover, the results were observed in a concentration dependent manner. So, the in-vitro studiesclearly showed that the methanolic extract of Bridelia scandens has a significant antioxidant activity. These invitro assays indicate that this plant extracts is a significant source of natural antioxidant, which might be helpful in preventing the progress of various oxidative stresses