Biochemical analysis of saliva of subjects with periodontal disease

The most common diseases of periodontal tissues are inflammatoryprocesses of gum and insertion of teeth normality associated to the local accumulation of teeth biofilm. The objective of this search is evaluating if the periodontal diseases are able to induce qualitative and quantitative alteration in saliva of subjects with periodontal diseases. Forty subjects,divided in 2 groups of 20, being one the control group (CG) and the other the test group (TG), based on age and sex were evaluated. There were analyzed the following salivary parameters: capacity of buffer, salivary flow speed, pH, calcium, urea and total proteins concentrations. The medium values and standard directions were: pH: CG 7.43 (± 0.62),TG 8.1 (± 0.49); salivary flow CG 1.21 (± 0.23); TG 1.01 (± 0.75);calcium CG 4.7 (± 1.2), TG 5.4 (± 0.85); urea CG 30.7 (± 9.6), TG 38.6(± 19.9); total proteins CG 355.5 (± 256.7), TG 299.2 (± 132.4).Significant rise in the amount of urea and calcium in the saliva of the periodontal disease individuals was observed whereas the amount of total proteins in the saliva of these individuals diminished, suggesting a change in microbiota. Salivary pH in the individuals of the TG is slightly higher of that of the CG. Salivary flow and capacity of buffer have been considered normal in both groups.