The analytic network process for the pharmaceutical sector: Multi criteria decision making to select the suitable method for the preparation of nanoparticles

The main goal was determined. The criteria and sub-criteria that affect the main goal were determined. The alternatives for the problem were determined. The interactions between criteria, sub-criteria, and alternatives respect to the main goal were determined. The super matrixes according to the network were assembled and then weighted super matrix and limit super matrix were then constructed. The values of this limit matrix are the desired priorities of the elements with respect to the goal. The alterative with the highest priority was finally chosen as the best alternative.The emulsion solvent diffusion technique (M-5) has the highest value (0.434379) among the alternative methods that are applicable to the preparation of the nanoparticles. The second highest is Polymer Precipitation (M-1) with a value of 0.178798, and the lowest value or last choice is Cross Linking (M-4) with a value of only 0.024516. The alternative with the highest priority would achieve the goal, i.e., the best method for the preparation of the nanoparticles.The alternative M5 emulsion solvent diffusion technique, scoring 0.434379 was the one with largest main concern amidst all the other alternatives and thereby judged to be the most apt procedure for the preparation of nanoparticles.Discovery and development of drugs for the remedy of diseases are a multidisciplinary locality that requires extends commitment to conduct technical research. Latest studies disclosed that the mean time to discover, develop and approve a new pharmaceutical in the united states takes roughly 14.2 years [1] with an approximated research expenditure of $800-$900 million in 2003 [2-4] and a separate analysis estimated the cost at $ 1.3-$1.6 billion in 2005 [5]. In the last few decades, Pharmaceutical formulations with Novel Drug Delivery System (NDDS) have been presented with the aim of optimizing bioavailability by modulating the time course of the drug concentration in body-fluid [6,7]. Novel drug-delivery systems