A new chinese restaurant syndrome: the 'chinese fondue' carbon monoxide mass intoxication

A traditional component of the Réunion island gastronomy, the chinese fondue, attracts many people. On 17 August 1996 (in the southern hemisphere winter) several children and then adults among 100 customers in a chinese restaurant suddenly presented dyspnea, nausea, vomiting, headache, confusion and clumsiness. Neither loss of consciousness nor syncope were noted. The victims (17 children, including an infant, mean age 10 ± 4 years, and 36 adults, including a pregnant woman, mean age 41 ± 10 years) were sitting around several chinese charcoal-pans cooking a chinese fondue. The atmosphere was confined, with closed windows and a non-functioning air conditioning system. The relief team removed the victims from the site of exposure, administered normobaric oxygen (10l/min), and evacuated them to the nearby hospital. Out of 53 subjects, two refused to undergo further medical attention and left the hospital, having received oxygen and before any blood samples were taken.After 60–90 min intensive oxygenation, the average level of COHb measured in patients was as follows (38 results only could be traced by the time of the study): one case, 12% (47-year-old female); eight cases, 10% (6-year-old male, 11-year-old female, 12-year-old female, 12-year-old male, 35-year-old female, 39-year-old female, 45-year-old male and 61-year-old female); one case, 7.4%; seven cases, 4.8%; and 21 cases, 2% or less.The CO intoxication was confirmed by the carboxyhemoglobin dosages, bearing in mind that the CO half-life decreases to 40–80 min when breathing 100% oxygen.As symptoms resolved with oxygen, there was no indication of hyperbaric oxygen therapy [2,3]. Nevertheless, the infant and the pregnant woman required treatment for several hours as fetal hemoglobin has a high affinity for carbon monoxide. Twenty-one victims were hospitalised for 12–24 h. All fully recovered.The clinical manifestations, although mild, the combustion of charcoal in a confined atmosphere, and the moderately elevate