Chiral Drug Separation by Supercritical Fluid Chromatography
超临界流体色谱法分离手性药物

Because of the high-efficiency, fast separation, low-temperature analysis and applicable to a wide variety of detectors , supercritical fluid chromatography (SFC ) is an attractive alternative for chiral drug separation. The development and application of this technique in enantiomer separation are reviewed with 48 references. The separation modes and the choices of experimental condition are discussed.