Technique and Application for Packing Preparative Liquid Chromatographic Column by Dynamic Axial Compression
制备型液相色谱动态轴向压缩柱技术和应用

The theory, installation, and installation design conditions for packing liquid chromatographic column by dynamic axial compression (DAC) are reviewed with 50 references cited. The effects of column length, the properties of packing materials, the properties of slurring solvents, and the pressure of compression on packing process and column performances are analyzed. The problems on density non-homogeneity in the column and the effect of column wall, and the methods for solving them are presented. The advantages and disadvantages of this technique, its applications, current state of development, and perspectives are discussed.