Preparation of bovine serum albumin immobilized adsorbent for specific adsorption of bilirubin
固定化牛血清白蛋白吸附材料的制备及其对胆红素的吸附性能

Serum bilirubin concentration is greatly elevated in certain diseases such as hyperbilirubinemia and severe hepatitis.Lowering the level of bilirubin is one of the major targets of many therapies such as plasma exchange and hemoperfusion.In this study,a bilirubin specific adsorbent was prepared by covalently immobilizing bovine serum albumin(BSA) onto macroporous poly(glycidyl methacrylate-co-trimethylolpropane trimethacrylate) microspheres.The resulting BSA immobilized adsorbent(BIA) demonstrated good perf...