DNA Polymorphism Analysis by Capillary Electrophoresis
毛细管电泳DNA片段多态性分析

A review is given here to describe the principle and methods of gene polymorphism analysis by capillary electrophoresis (CE). DNA length polymorphism and sequence polymorphism are very important phenomena in gene molecular biology. Some practical works of gene length polymorphism analysis and sequence polymorphism analysis are listed. SSCP and HPA methods detecting gene point mutations are demonstrated. Applications of gene polymorphism analysis by CE in clinical forensic and biological research are also discussed in this paper.