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色谱  1998 

New Development of Hydrophobic Interaction Chromatography and Its Applications in Biochemical Research
疏水色谱法的进展及其在生化研究中的应用

Keywords: hydrophobic interaction chromatography,stoichiometric displacement model,packings,biopolymer,separation and purification
HIC
,疏水色谱,固定相,生物大分子,分离

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Abstract:

This review is mainly concerned with the recent developments in (i) the retention mechanism of biopolymers in hydrophobic interaction chromatography (HIC); (ii) the synthesis of HIC packings, such as, the packings based on the inorganic and organic matrices, non porous packings and porous membranes; (iii) the applications of HIC in both purifications of biopolymers and biochemical research, such as, renaturation and refolding of some denatured proteins, the change in molecular conformation of biopolymers. The review includes 62 references and a table.

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