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色谱  2000 

Enantiomeric Separation of Ketoprofen on an Ovomucoid Column
卵类粘蛋白柱手性拆分酮基布洛芬

Keywords: high performance liquid chromatography,ovomucoid,ketoprofen and its methyl ester,chiral separation
高效液相色谱法
,卵类粘蛋白,酮洛芬及其甲酯,手性拆分

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Abstract:

The enantiomeric separation of ketoprofen in three mobile phase systems on an ovomucoid (OVM) chiral stationary phase (CSP) column was investigated Suitable chromatographic conditions for simultaneous separation of the two pairs of enantiomers of ketoprofen and its methyl ester were adopted All of the four compounds occuring in the process of enzymatic stereoselective hydrolysis or esterification can be simultaneously separated.

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