Monitoring the secretion from single cells with temporal and spatial resolution

The secretion from cells plays a significant role in life activites and in the fields of neurobiology, cell biology, clinic, pathology, pharmacology etc. Thus to investigate the secretion at the single cell level with the developing methods is a frontier cross-discipline research activity. The contents, methods and new progress of this research have been reviewed by electrochemical monitoring combined with patch-clamp techniques, fluorescent detection and immunoassay, and the prospects on the frontier of the research area have been discussed.