Cyclotrimerization of nitriles catalyzed by Li_3N
Cyclotrimerization of nitriles catalyzed by Li3N

Nitriles were unexpectedly trimerized into s-triazines or amino-pyrimidines in high yields in the presence of catalytic amount of Li3N, resulting in a simple, solvent-free and easy-to-scale-up one-pot way to synthesize s-triazines and 4-amino-pyrimidines with high yield.