Synthesis of a symmetrical tetrasubstituted cucurbit[6]uril and its host-guest inclusion complex with 2,2 ′-bipyridine
Synthesis of a symmetrical tetrasubstituted cucurbit[6]uril and its host-guest inclusion complex with 2,2′-bipyridine

Synthesis of a symmetrical tetrasubstituted cucurbit6]uril has been achieved by using the diether of dimethylglycoluril (1) and the dimmer of glycoluril (2). The structure of the symmetrical tetramethylcucurbit6]uril (TMeQ6]) has been determined by single crystal X-ray diffraction, 1H NMR spectroscopy and ESMS. The 1H NMR spectra of 2,2′-bipyridine added to TMeQ6] reveal that the host-guest inclusion complex was easily formed.