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计算机科学 2008
Survey on Computing Models for Haplotype Assembly Problem
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Abstract:
Haplotype detection has expansive application in inherited gene's orientation,medicine reaction's research and individual identification.The haplotype assembly problem is the computing problem of inducing a individual's haplotypes based on several optimal criteria from one's DNA fragments sequencing data.This paper made detailed research on such models as MSR,MFR,MEC,WMLF,MEC/GI and got conclusion as follows:in the case of no reading errors,the reconstruction rate of these models is basically identical.As t...