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计算机科学 2003
Neural Network Method for Protein Secondary Structure Prediction
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Abstract:
The explosive accumulation of protein sequences in the wake of large-scale sequencing projects is in shark contrast to the much slower experimental determination of protein structures. Neural Networks have been successfully applied into the prediction of protein structures, and the prediction accuracy continues to rise. This paper introduces the basic methods and technologies of the prediction of protein secondary structures using neural networks, especially expounds the two aspects: the improvement of neural network architecture and the adding of "evolutionary" information, which lead the ascent of prediction accuracy