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菌物学报 2012
Kinetic study of liquid fermentation for Metarhizium anisopliae IMI330189
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Abstract:
The liquid fermentation kinetics of Metarhizium anisopliae IMI330189 was observed. Kinetic models of biomass growth and substrate consumption were established based on Sigmoid model and the parameters of the models were determined by Origin7.5 software. The results showed that the models fitted well with the liquid fermentation process of M. anisopliae IMI330189. The maximum specific growth rate was found to be 0.084h-1 at 22.8h, specific total sugar consumption rate 0.246h-1 at 9.6h and specific total nitrogen consumption rate 0.007h-1 at 10.3h. The maximum yield coefficient of biomass from total sugar was 0.861g/g at 39.8h. The model simulation matched well with the experimental observations, which made it possible to elucidate the kinetic characteristics of M. anisopliae IMI330189 during liquid fermentation. These models thus can be employed for the development and optimization of M. anisopliae IMI330189 liquid fermentation processes.