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菌物学报  2011 

Antitumor active constituent in fruiting body of Phellinus yamanoi against Hepatoma H_(22) cell
山野木层孔菌子实体中抑制H_(22)荷瘤小鼠肿瘤的活性成分研究

Keywords: 山野木层孔菌,抑瘤活性,白介素-2,肿瘤坏死因子-α

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Abstract:

Three kinds of extracts were made from the fruiting body of Phellinus yamanoi by gradient extraction method using petroleum ether,methanol and water as extracting solution,and 4,6,8(14),22(23)-tetraen-3-one-ergostane was isolated from petroleum ether extract.The anti-tumor activities of the three extracts and the monomer compound against mice Hepatoma H22 were studied in vivo.Inhibition rates of tumor,immune organ indexes and the contents of immune factors were evaluated as indicators.The results showed tha...

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