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菌物学报  2011 

Purification, identification and antitumor activities of secondary metabolites from marine fungus Eutypella scoparia FS26
海洋真菌帚状弯孢聚壳FS26代谢产物的分离鉴定与抗肿瘤活性研究

Keywords: marine fungus,Eutypella scoparia,chromatographic methods,recrystallization,cytochalasan family
海洋真菌,帚状弯孢聚壳,色谱技术,重结晶,细胞松弛素类

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Abstract:

By various chromatographic methods(silica gel,reverse silica gel,Sephadex LH-20 and so on) and recrystallization,six compounds were isolated from the culture of the marine fungus Eutypella scoparia,which was isolated from the sediment of the South China Sea.By extensive NMR analysis as well as comparison with literature reports,the structures of compounds 1-6 were established as(3S,3aR,7aS)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one(1),rel-(3S,6S,7R,10R)-7,10-epoxy-3,7,11-trimethyldodec-1-ene-3,6...

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