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菌物学报  2011 

Recent progresses in the studies of taxol and taxane-producing fungi
真菌紫杉醇/烷研究近况

Keywords: taxol,taxanes,taxol-producing fungi,terpene
紫杉醇,紫杉烷,内共生真菌,萜类

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Abstract:

Paclitaxel (taxol?), a member of taxane family, has become a widely used anticancer drug in clinic. The industrial fermentation of taxol by fungi promises an effective way to increase the production and supply of the drug in the market. This review summarizes the latest results of the biodiversity of taxol-producing fungi, the fungal taxonomy, purification and characterization of fungal taxol, and molecular genetics of taxol biosynthesis.

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