Recent research advances on endophytic fungi producing taxol
内生真菌产紫杉醇研究的回顾与展望

Taxol with high efficiency, low toxicity and broad-spectrum is one of the most effective natural anti-cancer drugs for the coming 20 years. Recent studies have found that taxol from the fermentation of endophytic fungi of plants has been demonstrated a high potential for efficient production of taxol. Summarize recent research advances in the technique of fermentation producing taxol including biodiversity of taxol-producing endophytic fungi, isolation of the fungi, and the techniques of taxol extraction. The pathways to improve the production of taxol by endophytic fungal were also comprehensively discussed. Along with the development of molecular biology techniques and fermentation engineering, the large-scale fermentation to produce taxol is hopefully realizable.