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Molecules  2010 

Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential

DOI: 10.3390/molecules15010012

Keywords: carbohydrates, furan derivatives, cytotoxic activity, anti-tumor, apoptosis

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Abstract:

In our search for new anticancer therapies, some compounds synthesized in our lab were selected and their potential cytotoxic activity was evaluated in vitro against two cancer cells lines including a solid tumor (UACC-62, melanoma) and a human lymphoma (JURKAT). Compounds showing cytotoxic activity were subjected to an apoptosis assay. Two compounds showed promising results.

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