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Molecules  2009 

Phosphotungstic Acid: An Efficient, Cost-effective and Recyclable Catalyst for the Synthesis of Polysubstituted Quinolines

DOI: 10.3390/molecules14031126

Keywords: Heteropolyacid, Heterogeneous catalysis, Friedl?nder annelation, Quinoline

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Abstract:

Phosphotungstic acid (H3PW12O40) was used as an efficient and recyclable catalyst for the synthesis of polysubstituted quinolines through the Friedl?nder condensation of 2-aminoarylketone with carbonyl compounds, which was achieved by conventional heating under solvent-free conditions.

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