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Molecules 2006
A Simple Synthetic Route to Methyl 3-Fluoropyridine-4-carboxylate by Nucleophilic Aromatic SubstitutionDOI: 10.3390/11020130 Keywords: Methyl 3-fluoropyridine-4-carboxylate, methyl 3-nitropyridine-4-carboxylate, fluoride anion, nucleophilic aromatic substitution. Abstract: The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoro- pyridine-4-carboxylate 2.
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