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Molecules 2000
A Short Review on Cardiotonic Steroids and Their Aminoguanidine AnaloguesDOI: 10.3390/50100051 Keywords: Digitalis glycosides analogues, structure-activity relationships, inotropic activity, Na+, K+-ATPase, aminoguanidine analogues Abstract: A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.
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