Synthesis of Sultam Derivatives with Expected Biological Activity. 15

4-(Trihydro-2H-1,2-thiazole-1,1-dioxide-2-yl)benzophenone (1), 4-(3,5-dimethyl-1`,2`-thiazine-1`,1`-dioxide-2-yl)benzophenone (2), and 4-(tetrahydro-2H-1,2-thiazine-1,1-dioxide-2-yl)benzophenone (6) were obtained from 4-aminobenzophenone and the appropriate reagents. Isomeric (E-) and (Z-) 2-Ethoxycarbonyl-4-phenyl-4-(4-tetrahydro-1,2-thiazine-1,1-dioxide-2-yl)phenyl-3-butenoic acids (11 and 12) and 2-carboxy-4(N-phenylthiocarbamoyl)-1-phenyl-6-(tetrahydro-2H-1,2-thiazine-1,1-dioxide-2-yl)naphthalene (16) were also synthesized.