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海洋科学  2011 

Bacteriostatic action of 11 fluoroquinolones to bacterium Aeromonas hydrophila
动物专用喹诺酮类药物对嗜水气单胞菌体外抑菌作用的研究

Keywords: Fluoroquinolone(FQs),Aeromonas hydrophila,minimum inhibitory concentration,minimum bacteriacidal concentration
氟喹诺酮
,嗜水气单胞菌(Aeromonas,),最小抑菌浓度,最小杀菌浓度

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Abstract:

In this experiment, agar diffusion method was used to study antibacterial effect of 11 fluoroquinolones(FQs)on Aeromonas hydrophila. The inhibition zone was measured, and the double tube dilution method was used to study minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The results showed that Levofloxacin hydrochloride, Ofloxacin, and Sarafloxacin hydrochloride had better antibacterial effect on A. hydrophila, and the MIC of the three medicines were 0.012, 0.024, 0.024mg/L, respectively. The Enrofloxacin lactate, Enrofloxacin hydrochloride, and Ofloxacin had the same MBC value of 1.563 mg/L.

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