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海洋科学  2010 

The in vitro dissolution of algal polysaccharide hard shell capsules
海藻多糖空心胶囊药物溶出度研究

Keywords: plant capsules,gelatin capsules,in vitro dissolution
植物空心胶囊
,明胶空心胶囊,药物溶出度

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Abstract:

Algal polysaccharide hard shell capsule is a kind of plant capsule mainly containing algal polysaccharide extracted from marine Rhodophyte and plant cellulose. The performances of in vitro dissolution of cefalexin, azithromycin, and ibuprofen of algal polysaccharide hard shell capsules have been investigated respectively and compared with that of gelatin capsules. This study confirmed that algal polysaccharide hard shell capsules were superior or equal to gelatin capsules in ultimate dissolution rates and accelerated stabilities. In this way, algal polysaccharide hard shell capsules can therefore be considered as a viable alternative to gelatin capsules.

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