Synthesis and bioactivity of 3-carbonyl-benzo[d]isothiazol-3(2H)-methyl Benzoates Derivatives
苯并异噻唑啉酮类衍生物的制备与生物活性测试

Novel antifoulants were synthesized and their structures were confirmed by means of MS, elemental analysis, and 1H NMR. The antimicrobial activity of the compounds on five bacteria, including Escherichia coli, Staphyloccus aurueus, Vibrio alginolyticus, Aeromonas hydrophila, and Bacillus subtilis were tested. These compounds showed good antimicrobial activity, especially to Escherichia coli. When the compounds concentration were reached 10-6 g/L the viable cell were reduced by more than 90%. The novel synthesized compounds might be potential microbial inhibitors.