INFLUENCE OF HETEROZYGOTE MORTALITY FOR RESISTANCE ON EVOLUTION OF INSECTICIDE RESISTANCE
害虫抗性杂合子死亡率对抗性进化的影响

The effects of changes of heterozygote in the absence and presence of insecticides and the degree of its dominance on evolution in three different combinations of R allel frequency and population size were investigated by computer simulation. The results showed that in all combinations, the reversion of R allel in the absence of insecticide was a slow process except for RR and RS phenotypes with low biotic fitness. The lower the fitness value, the faster the resistance reversed. Evolution of resistance to insecticides could be controlled when high dosage of insecticide sufficient to kill all or most heterozygote was used in the presence of a small influx of susceptible immigrants. Once resistances was obvious, it would make this strategy no longer effective.