Killing bacteria of titanium(IV) and copper co-doped hydroxyapatite film under weak UV light
Ti(IV)与铜离子共掺杂的羟基磷灰石薄膜弱紫外光杀菌研究

Hydroxyapatite (Ca10(PO4) 6(OH) 2: HAP) particles co-doped with Ti(IV) and Cu2+(HAPTiCu), by a coprecipitation and ion-exchange methods. The Gram-negative Escherichia coli was selected the model to evaluate the bactericidal killing activity of different films on porous spumous nickel under weak UV light. The results indicated that HAPTiCu had very highly efficiency bactericidal activity and much higher than that of HAPTi and P25 TiO2 under weak UV light. This was contributed to the synergy of the Ti(IV) photocatalytic decomposition activity and the Cu2+ antibacterial activity in the structure of HAPTiCu. ESR studies indicated that O-2 reactive species were invoved in the reaction. Most of the released Cu2+ from HAPTiCu films were deposited on the surface of HAPTiCu during photocatalytic killing bacteria process, only fewer remained in the reaction solution, keeping the stability of the material.