Assessment acute and chronic toxicity and endocrine disruption effects of whole effluent based on early stage development of Japanese medaka (Oryzias latipes)
利用日本青鳉早期发育阶段暴露评估排水的急、慢性毒性和内分泌干扰效应

A bioassay protocol for screening acute and chronic toxicity and endocrine disrupting of whole effluent based on early stage development of Japanese medaka (Oryzias latipes) was established and recommended. This protocol belonged to in vivo and partial life stage test. The period of the test was 21 days. The protocol had many advantages such as not depending on expensive apparatus, simple to operate, low cost and multiple outputs. In the paper, the proposed protocol was applied to test potential ecotoxicological risks of typical sewage effluent and industrial wastewater discharges in Beijing city. The results showed that acute and chronic toxicity, teratogenicity and endocrine disrupting could be detected in the sewage effluent and industrial waste water. In comparison of different advanced treatment processes aiming at detoxication, it was found that reverse osmosis could remove most of the toxicants from the waters.