Effects of long-term exposure of low-level 2,4-dichlorophenol on the antioxidant defense system in liver of Carassius auratus
2,4-二氯苯酚低浓度长期暴露对鲫鱼肝脏抗氧化系统的影响

Under the indoors simulant conditions, the effects of long-term exposure of low-level 2,4-Dichlorophenol on the antioxidant system of larval fishes were studied. The results showed that the activities of catalase (CAT), sedium-dependent glutathione peroxidase (Se-GPx) and the content of oxidized glutathione (GSSG) were induced significantly. The activity of superoxide dismutase (SOD) was induced remarkably when 2,4-Dichlorophenol level was at only 0.005 mg.L-1; the content of reduce glutathione (GSH) was almost suppressed continuously; the activity of glutathione reductase was inhibited firstly and then restored gradually; the activity of glutathione S-transferase (GST) had slight variances among groups. GR, GSH, especially SOD, can act as an early monitoring index of 2,4-Dichlorophenol pollution in aquatic ecosystem.