Screening of the Precursors of Strong Mutagen by Chlorination of Fractions from Yangtze River Water
长江水体氯化过程中强致突变物前驱物的筛选

The strong mutagen,3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone]MX,was found to be one of the most potent mutagens in chlorinated drinking water.In this study,dissolved organic matters from Yangtze River water were separated into several compound classes by sorbtion on a series of resin absorbents,respectively.After chlorine treatment of the fractions,MX was determined with GC/MS in the selected ion monitoring mode.The results indicated that the humic substances are the most important precursor in the natural waters.Some phenols,aldehydes,aromatic acids and ketones detected in the oxidation products of humic substances and other fractions might play an important role in the formation of MX.