|
环境科学 1990
Application of Inductest in Research of Environmental Mutagens
|
Abstract:
The possible mutagenic activity of 35 different chemicals has been tested with inductest, in which S9 mixture was used as a metabolizing system. The results showed that 13(37%)chemicals had mutagenic activity, 10 of these chemicals gave positive reaction in inductest in the presence of S9 mixture, three chemicals gave positive reaction in inductest in the presence of S9 mixture or without it. Some of the chemicals are known as potent mutagens and carcinogens(aflatoxin B1)or anticancer drugs(mitomycin C). It is considered that inductest is an ef-fective method in research of environmental mutagens.