Nowadays the adjustment of medication for each patient is at the center of health strategy. Children can be considered as specific targets with their own specificities. In the oral route field some examples of drugs especially adapted to children can be found. Design is introduced in drug formulation to offer a better choice of products and now, children can be considered as partners in their own treatment. Enhanced comprehension of children's requirements can also lead to creation of drugs that improve compliance.
References
[1]
Cardot, J.M. Drug delivery approaches for the paediatric population. 9th European Partnership and Latest Innovation in Drug Delivery, Informa, Bruxelles, Belgium, 23–24 November 2010.
[2]
PHARMATERMMD. Bulletin terminologique de l'industrie pharmaceutique. Tranches d'age en pédiatrie, 2010, 21. no. 1. Available online: www.groupetraduction.ca/documents/Vol21no12010.pdf (accessed on 29 November 2011).
[3]
Draft Guideline on Pharmaceutical Development of Medicines for Paediatric Use; European Medicine Agency: London, UK, 2011. EMA/CHMP/QWP/180157/2011.
[4]
Walsh, J.; Bickmann, D.; Breitkreutz, J.; Chariot-Goulet, M.; European Paediatric Formulation Initiative (EuPFI). Delivery devices for the administration of paediatric formulations: overview of current practice, challenges and recent developments. Int. J. Pharm. 2011, 415, 221–231.
[5]
Aiache, J.M.; Gauthier, P. Suitable dosage forms for paediatric medicine. W.H.O Training Workshop on Pharmaceutical Development with a Focus on Paediatric Formulations, Tallinn, Estonia, 15–19 October 2007.
[6]
Committee for Medicinal Product for Human Use (CMPH). In Reflection Paper: Formulations of Choice for the Paediatric Population; European Medicines Agency (EMA): London, UK, 2006. EMEA/CHMP/PEG/194810/2005.
[7]
Hoffart, V. Les développements d'une forme pédiatrique de spironolactone composée de nanocapsules. MD Pharmacie Thesis, Univ Auvergne, Clermont-Ferrand, France, 2010.
[8]
Symposium Médicament pédiatrique et ses spécificités–Design-moi un medicament, France, 21–22 March 2002.
[9]
Gauthier, P. Formulation and packaging design for NCE, examining specific population and product repositioning. 9th European Partnership and Latest Innovation in Drug Delivery, Informa, Bruxelles, Belgium, 23–24 November 2010.
[10]
Gauthier, P. Using Design in Pharma Packaging for Improving Compliance and Avoiding Overconsumption. UBM Canon: Paris, France, 2011.
[11]
Breitkreutz, J. European perspectives on pediatric formulations. Clin. Ther. 2008, 30(11), 2146–2154.
[12]
Rodriguez, W.; Selen, A.; Avant, D.; Chaurasia, C.; Crescenzi, T.; Gieser, G.; Di Giacinto, J.; Huang, S.M.; Lee, P.; Mathis, L.; Murphy, D.; Murphy, S.; Roberts, R.; Sachs, H.C.; Suarez, S.; Tandon, V.; Uppoor, R.S. Improving pediatric dosing through pediatric initiatives: what we have learned. Pediatrics 2008, 121(3), 530–539.
[13]
Cram, A.; Breitkreutz, J.; Desset-Brèthes, S.; Nun, T.; Tuleu, C.; European Paediatric Formulation Initiative (EuPFI). Challenges of developing palatable oral paediatric formulations. Int. J. Pharm. 2009, 365, 1–3.
[14]
Llorca, P.M. Discussion of prevalence and management of discomfort when swallowing pills: orodispersible tablets expand treatment options in patients with depression. Ther. Deliv. 2011, 2(5), 611–622.
[15]
Nunn, T.; Williams, J. Formulation of medicines for children. Br. J. Clin. Pharmacol. 2005, 59(6), 674–676.
[16]
Young, L.; Lawes, F.; Tordoff, J.; Norris, P.; Reith, D. Access to prescribing information for paediatric medicines in the USA: post-modernization. Br. J. Clin. Pharmacol. 2009, 67(3), 341–346.
[17]
Uvesterol vitamine ADEC. Available online: www.afssaps.fr/var/…/645b2112293b82daa787c16d618ccdea.pdf (accessed on 29 November 2011).
[18]
Matthieu lehanneur. Available online: http://www.mathieulehanneur.fr/ (accessed on 29 November 2011).
[19]
Dose, sip, safe…. World Pharm Frontiers 2010, 2, 128.
[20]
Flackpull–Flacon entube, packaging pour produits cosmétiques. Available online: www.flackpull.fr/ (accessed on 29 November 2011).
[21]
Amcor Flexibles Awarded 2008 Flexible Packaging…-Qmed. Available online: www.qmed.com/…/amcor-flexibles-awarded-200 (accessed on 29 November 2011).
[22]
CADI Hors série/Special Issue 2008. pp. 29–35. Available online: www.lecolededesign.com/ressources/CADI_hors_serie_2008.pdf (accessed on 29 November 2011).
[23]
Gauthier, P. Le médicament pédiatrique aujourd'hui. Doses 2008, 31, 26–31.
