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OALib Journal期刊
ISSN: 2333-9721
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HYDROGELS PREPARED FROM ACRYLATES HAVING PYRROLIDONO-MOIETY
由含吡咯烷酮基丙烯酸酯类所得水凝胶的性质

Keywords: N-pyrrolidonoethyl acrylate(PyEA),2-N-pyrrolidonoethyl methacrylate(PyEMA),Hydrogel,Equilibrium water content(EWC),Release behavior
甲基丙烯酸
,吡咯烷酮基乙酯,水凝胶,羟乙酯

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Abstract:

lightly crosslinked hydrogels prepared from 2-N-pyrrolidonoethyl acrylate(PyEA) and 2-N-pyrrolidonoetbyl metLacrylate(PyEMA) exhibited high equilibrium water content (EWC) up to 80.9gb. The Lydrophilicity of P(PyEA-coHEMA) and P(PyEMA-co-HEMA) was much better than that of PHEMA. The release of 5(6)-carboxyfluorescein which acts as a probe from the kydrogels displayed normal behavior controlled by diffusion and the release rate of 5(6)-carboxyfluore.seem appeared to be those of Fickian release kinetics.

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