FLUORESCENCE STUDY OF POLY-(ACETYL SALICYLIC ACID-GLYCIDYL METHACRYLATE) DURING THE COURSE OF HYDROLYSIS
高分子化的阿司匹灵在水解过程中的荧光研究

The process of hydrolysis of both aspirin and the title copolymer was studied by fluorescence spectra. Our results showed that a large variation of rate of hydrolysis may occur when aspirin is immobilized to a polymer support.By comparing the fluorescence spectra and hydrolysis rate of both aspirin and methyl salicylate, it can be concluded that in a sequence of reactions from copolymer to salicylic acid, the acetyl group of the copolymer is first cleaved, and then followed by the cleavage ester link with the formation of salicylic acid.