Preparation of Gigaporous P(MMA-MAA) Microspheres by Two-step Emulsification,Emulsion Ripening and Solvent Extraction
复乳液滴模板法结合溶剂去除法制备P(MMAMAA)超大孔聚合物微球

P(MMA-MAA) was used as the major component of particle material and amphiphilic polymer PELA as a complementary material.Gigaporous poly(methyl methacrylate-methacrylic acid) P(MMA-MAA)] microspheres with flow-through pores with the diameters from submicron to micron scale were prepared by two-step emulsification,emulsion ripening and solvent extraction.The influential parameters on final morphology were particularly investigated,including the polymer component,ripening time and osmotic gradient.Under the optimum preparation conditions of P(MMA-MAA) concentration 100 g/L,PELA amount 40 g/L,PVA concentration in W2 25 g/L,NaCl concentration in W1 1%~5 g/L and emulsion ripening time 0~30 min,the microspheres with pore size at micron scale and porosity of 95% were obtained.The formation mechanism of gigapores was discussed with consideration of the evolution behavior of double-emulsion system.The rigidity of microspheres could be improved by cross-linking after the formation of porous particles.