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光子学报  2006 

Compare for Calibration Methods to Optical Trapping Force Upon Non-spherical Biological Cells
两种非球形细胞光镊阱力标定方法的比较

Keywords: Boltzman distribution,Optical tweezers,Trapping stiffness,Biological cells
玻尔兹曼分布
,光镊,光阱刚度,生物细胞

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Abstract:

Both Boltzmann distribution method(BDM) and mean square displacement method(MSDM)are available for the force calibration of non-spherical biological cells in a harmonic optical trap. These two calibration methods were compared with numeric experiments. Results indicate that comparing with MSDM, BDM is not only available for the force calibration of non-spherical or anisotropic cells, but also for irregular cells in optical trap potential with inharmonic and asymmetric profiles.The results agree with the experiments reported.

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