INDUCED DEVELOPMENT OF PIGMENT MACROPHAGE AGGREGATE(PMA)IN ADULT AND JUVENILE OF THE FRESHWATER CATFISH
鲇鱼成鱼和幼鱼中含色素的巨噬细胞集结的诱导发生

The development of PMA in adult and juvenile of Silurus asotus was investigated by peritoneally injecting with different dosages of bovine serum albumin(BSA)or Indian ink to stimulate macrophage(m)activity.The m heterogeneity was demonstrated in lymphomyeloid tissue(LT)as well as in liver with histologic and cytochemic approaches,by which 5 types of ms,i.e.reticular/fibrous macrophage(RFm),shuttle macrophage(Sm),round red macrophage(RRm),round yellow-red macrophage(RYRm)and pigment macrophage(PM),were identified.PM originated from RFms through the intermediate stages of Sm,RRm and RYRm.The total amount of round macrophages(Rms)and PMA formation was closely related,PMA could not form if the amount of Rms was not high enough,and PMA had a tendency of migrating out of LT during the lateexperiment.The functions attributed to PMA were discussed.