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光子学报  2005 

Study of the Key Technology of Optical Fiber Biosensor
光纤生物免疫传感器原理及关键技术研究

Keywords: Biosensor,Spectrometer,Optical fiber biosensor,Immune dynamics study
生物传感器
,光谱仪,光纤传感器,免疫检测

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Abstract:

By using of the Rifs (Reflectometric Interference Spectroscopy) system and the testing result of AFM (atomic force microscope), a novel method for directly monitoring the change of reflectometric spectrum extremum during antigen-antibody interactions is proposed. Experiments show that the process of immunoreactions can be directly monitored and the results can be saved continuously by this method. Compared with film thickness extremun method, this method is simple, sensitive and effective for immune dynamics study.

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