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中华医学超声杂志(电子版) 2010
Abnormal myocardial perfusion in subendocardial and subepicardial layers of hypertrophied myocardium by myocardial contrast echocardiography
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Abstract:
Objective The abnormal microcirculation flow perfusion across the left ventricular wall of hypertrophied myocardium by myocardial contrast echocardiography(MCE) was evaluated to reveal microvascular dyfunction in early stages of left ventricular hypertrophy(LVH).Methods A group of twenty-six mice had LVH via abdominal aortic coarctation(AC) and a group of 13 mice with shammed operation as group sham-operation group(SH) were raised for 4 weeks and 8 weeks respectively.MCE was performed in each group.Regions ...