全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Gamma Hydroxybutyric Acid (GHB) for the Treatment of Alcohol Dependence: A Review

DOI: 10.3390/ijerph6061917

Keywords: gamma-hydroxybutyric acid, alcohol withdrawal syndrome, anti-craving drug

Full-Text   Cite this paper   Add to My Lib

Abstract:

Gamma-hydroxybutyric acid (GHB) is a short-chain fatty acid structurally similar to the inhibitory neurotransmitter γ-aminobutyric acid. Clinical trials have demonstrated that 50-100 mg/kg of GHB fractioned into three or six daily doses is able to suppress alcohol withdrawal symptoms and facilitates the maintenance of abstinence from alcohol. These studies have also shown that GHB craving episodes are a very limited phenomenon (about 10-15%). Thus, physicians with access should consider the clinical efficacy of GHB as a valid pharmacological tool for the treatment of alcohol addiction.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133